/* ═══════════════════════════════════════
   AbAnalyzer Pro — Design System
   ═══════════════════════════════════════ */
:root {
  --navy: #1C1F2E;
  --navy-light: #272B3D;
  --navy-mid: #22263A;
  --accent: #D4883A;
  --teal-light: #E0A35C;
  --teal-dim: rgba(212,136,58,0.10);
  --teal-glow: rgba(212,136,58,0.20);
  --surface: #FAFAF8;
  --surface-alt: #F2F1EE;
  --surface-hover: #EBEAE6;
  --card: #FFFFFF;
  --border: #D8D6D0;
  --border-light: #EBEAE6;
  --text: #2A2D3A;
  --text-secondary: #5A5D6E;
  --text-muted: #8C8F9E;
  --danger: #C4473A;
  --warning: #D4943A;
  --success: #3A8C5C;
  --purple: #7B61C4;
  --sidebar-w: 260px;
  --sidebar-collapsed: 64px;
  --header-h: 64px;
  --radius: 8px;
  --radius-sm: 5px;
  --shadow-sm: 0 1px 3px rgba(28,31,46,0.06);
  --shadow-md: 0 4px 16px rgba(28,31,46,0.08);
  --shadow-lg: 0 8px 32px rgba(28,31,46,0.12);
  --font-body: 'DM Sans', 'Noto Sans SC', sans-serif;
  --font-mono: 'JetBrains Mono', monospace;
  --transition: 0.25s cubic-bezier(0.4,0,0.2,1);
}

*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }

html { font-size: 14px; }
body {
  font-family: var(--font-body);
  background: var(--surface-alt);
  color: var(--text);
  overflow: hidden;
  height: 100vh;
}

/* Scrollbar */
::-webkit-scrollbar { width: 6px; height: 6px; }
::-webkit-scrollbar-track { background: transparent; }
::-webkit-scrollbar-thumb { background: var(--border); border-radius: 3px; }
::-webkit-scrollbar-thumb:hover { background: var(--text-muted); }

/* ── AUTH OVERLAY — Landing page (UmabsDB-style layout) ── */
.auth-overlay {
  position: fixed; inset: 0; z-index: 1000;
  display: none;
  background: linear-gradient(155deg, #F0F7FB 0%, #E4F1F8 40%, #C8E6F2 100%);
  overflow: hidden;
}
.auth-overlay.active { display: block; }

.auth-page-scroll {
  position: relative; z-index: 2;
  height: 100vh; overflow-y: auto; overflow-x: hidden;
  scroll-behavior: smooth;
}

#dnaCanvas {
  position: fixed; inset: 0;
  width: 100%; height: 100%;
  opacity: 0.06; z-index: 1;
  pointer-events: none;
}

/* ── Navbar ── */
.auth-navbar {
  position: sticky; top: 0; z-index: 20;
  background: rgba(255,255,255,0.82);
  backdrop-filter: blur(16px);
  border-bottom: 1px solid rgba(0,80,120,0.06);
  padding: 0 32px;
}
.auth-navbar-inner {
  max-width: 1200px; margin: 0 auto;
  display: flex; align-items: center; justify-content: space-between;
  height: 60px;
}
.auth-nav-brand {
  display: flex; align-items: center; gap: 10px;
}
.auth-nav-logo-svg { width: 36px; height: 36px; }
.auth-nav-name {
  font-size: 1.2rem; font-weight: 700; color: #0B3D5C;
  display: block; line-height: 1.2;
}
.auth-nav-name em { font-style: normal; color: #1A7FA8; font-weight: 300; }
.auth-nav-tagline {
  font-size: 0.68rem; color: #6A8EA5; letter-spacing: 0.5px;
}
.auth-nav-actions { display: flex; gap: 10px; }
.auth-nav-btn {
  padding: 7px 22px; border-radius: 6px;
  font-family: var(--font-body); font-size: 0.88rem; font-weight: 600;
  cursor: pointer; transition: all 0.2s ease;
}
.auth-nav-login {
  background: none; border: 1.5px solid #1A7FA8; color: #1A7FA8;
}
.auth-nav-login:hover { background: rgba(26,127,168,0.06); }
.auth-nav-signup {
  background: #1A7FA8; border: 1.5px solid #1A7FA8; color: #fff;
}
.auth-nav-signup:hover { background: #15698E; }

/* ── Hero split layout ── */
.auth-hero-split {
  max-width: 1200px; margin: 0 auto;
  display: flex; align-items: center;
  padding: 60px 32px 50px;
  gap: 40px;
  min-height: calc(100vh - 180px);
  animation: heroFadeIn 0.8s ease-out;
}
@keyframes heroFadeIn {
  from { opacity: 0; transform: translateY(16px); }
  to { opacity: 1; transform: translateY(0); }
}
.auth-hero-left {
  flex: 1; max-width: 480px;
}
.auth-hero-title {
  font-size: 2.8rem; font-weight: 800;
  color: #0B3D5C; line-height: 1.15;
  letter-spacing: -1px;
  margin-bottom: 20px;
}
.auth-hero-desc {
  font-size: 0.92rem; color: #3B6A82;
  line-height: 1.7; margin-bottom: 8px;
}
.auth-hero-desc-en {
  font-size: 0.82rem; color: #7A9DB0;
  line-height: 1.6; margin-bottom: 28px;
}
.auth-hero-btns { display: flex; gap: 12px; }
.auth-hero-btn-primary {
  padding: 12px 28px;
  background: linear-gradient(135deg, #1A7FA8, #2B9CC5);
  color: #fff; border: none; border-radius: 8px;
  font-family: var(--font-body); font-size: 0.92rem; font-weight: 600;
  cursor: pointer; transition: all 0.25s ease;
  box-shadow: 0 2px 12px rgba(26,127,168,0.25);
}
.auth-hero-btn-primary:hover { transform: translateY(-2px); box-shadow: 0 6px 20px rgba(26,127,168,0.35); }
.auth-hero-btn-outline {
  padding: 12px 28px;
  background: none; border: 1.5px solid #3B7D9A; color: #3B7D9A;
  border-radius: 8px; font-family: var(--font-body); font-size: 0.92rem;
  font-weight: 600; cursor: pointer; transition: all 0.25s ease;
}
.auth-hero-btn-outline:hover { background: rgba(59,125,154,0.06); }

/* ── Right side: stats ring with rotating antibody ── */
.auth-hero-right {
  flex: 1; display: flex; justify-content: center; align-items: center;
}
.auth-stats-ring {
  position: relative;
  width: 460px; height: 460px;
}
.auth-ab-img {
  position: absolute;
  top: 50%; left: 50%;
  width: 260px; height: 260px;
  transform: translate(-50%, -50%);
  object-fit: contain;
  animation: abSpin 24s linear infinite;
  opacity: 0.55;
  filter: drop-shadow(0 4px 20px rgba(0,60,90,0.12));
}
@keyframes abSpin {
  from { transform: translate(-50%, -50%) rotate(0deg); }
  to { transform: translate(-50%, -50%) rotate(360deg); }
}
.auth-stat {
  position: absolute;
  text-align: center;
  animation: statPop 0.6s ease-out backwards;
}
.auth-stat-tl { top: 10px; left: 30px; animation-delay: 0.2s; }
.auth-stat-tr { top: 10px; right: 30px; animation-delay: 0.35s; }
.auth-stat-bl { bottom: 20px; left: 30px; animation-delay: 0.5s; }
.auth-stat-br { bottom: 20px; right: 30px; animation-delay: 0.65s; }
@keyframes statPop {
  from { opacity: 0; transform: scale(0.8); }
  to { opacity: 1; transform: scale(1); }
}
.auth-stat-label {
  font-size: 0.82rem; font-weight: 700; color: #0B3D5C;
  margin-bottom: 4px;
}
.auth-stat-icon {
  width: 40px; height: 40px; margin: 0 auto 2px;
  color: #D4883A;
}
.auth-stat-icon svg { width: 100%; height: 100%; }
.auth-stat-num {
  font-size: 2.4rem; font-weight: 800;
  color: #D4883A; line-height: 1;
}

/* ── Features ── */
.auth-features {
  padding: 48px 32px 52px;
  max-width: 1100px; margin: 0 auto;
  animation: featSlide 0.8s ease-out 0.3s both;
}
@keyframes featSlide {
  from { opacity: 0; transform: translateY(20px); }
  to { opacity: 1; transform: translateY(0); }
}
.auth-features-title {
  text-align: center;
  font-size: 1.4rem; font-weight: 700;
  color: #0B3D5C; margin-bottom: 28px;
}
.auth-features-grid {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: 18px;
}
.auth-fcard {
  background: rgba(255,255,255,0.82);
  backdrop-filter: blur(8px);
  border: 1px solid rgba(255,255,255,0.9);
  border-radius: 12px;
  padding: 24px 20px 20px;
  text-align: center;
  box-shadow: 0 2px 16px rgba(0,60,100,0.06);
  transition: transform 0.3s ease, box-shadow 0.3s ease;
}
.auth-fcard:hover {
  transform: translateY(-4px);
  box-shadow: 0 8px 28px rgba(0,60,100,0.12);
}
.auth-fcard-icon {
  width: 56px; height: 56px;
  margin: 0 auto 12px;
  background: linear-gradient(135deg, #E8F6FC, #D0EFF9);
  border: 2px solid rgba(75,184,212,0.2);
  border-radius: 50%;
  display: flex; align-items: center; justify-content: center;
  color: #1A7FA8;
}
.auth-fcard-icon svg { width: 28px; height: 28px; }
.auth-fcard h3 {
  font-size: 0.92rem; font-weight: 700;
  color: #0B3D5C; margin-bottom: 2px;
}
.auth-fcard h4 {
  font-size: 0.78rem; font-weight: 500;
  color: #6A8EA5; margin-bottom: 8px;
}
.auth-fcard p {
  font-size: 0.78rem; line-height: 1.5;
  color: #5A7D90; margin: 0;
}

/* ── Auth Modal ── */
.auth-modal-mask {
  display: none;
  position: fixed; inset: 0; z-index: 100;
  background: rgba(11,61,92,0.35);
  backdrop-filter: blur(4px);
  align-items: center; justify-content: center;
}
.auth-modal-mask.active { display: flex; }
.auth-modal-mask .auth-container {
  position: relative;
  width: 420px; max-width: 92vw;
  background: #fff;
  border: 1px solid rgba(0,80,120,0.08);
  border-radius: 16px;
  padding: 36px 32px;
  color: #1C2A3A;
  box-shadow: 0 12px 48px rgba(0,60,100,0.18);
  animation: modalIn 0.35s ease-out;
}
@keyframes modalIn {
  from { opacity: 0; transform: translateY(20px) scale(0.96); }
  to { opacity: 1; transform: translateY(0) scale(1); }
}
.auth-modal-close {
  position: absolute; top: 12px; right: 16px;
  background: none; border: none;
  font-size: 1.6rem; color: #9CBDD0; cursor: pointer;
  line-height: 1; padding: 4px;
  transition: color 0.2s;
}
.auth-modal-close:hover { color: #0B3D5C; }
.auth-modal-brand {
  text-align: center; margin-bottom: 20px;
}
.auth-modal-brand h2 {
  font-size: 1.4rem; font-weight: 700; color: #0B3D5C;
}
.auth-modal-brand h2 em { font-style: normal; color: #1A7FA8; font-weight: 300; }

.auth-tabs {
  display: flex; gap: 0; margin-bottom: 20px;
  border-bottom: 2px solid rgba(0,80,120,0.06);
}
.auth-tab {
  flex: 1; background: none; border: none;
  color: #8AACBD;
  font-family: var(--font-body); font-size: 0.92rem; font-weight: 600;
  padding: 10px 0; cursor: pointer; position: relative;
  transition: color 0.2s;
}
.auth-tab:hover { color: #0B3D5C; }
.auth-tab.active { color: #1A7FA8; }
.auth-tab.active::after {
  content: ''; position: absolute; bottom: -2px; left: 10%; right: 10%;
  height: 2.5px; background: #1A7FA8; border-radius: 2px;
}

.auth-form { display: none; flex-direction: column; gap: 14px; }
.auth-form.active { display: flex; }
.auth-form .form-group label {
  display: block; font-size: 0.78rem; font-weight: 600;
  color: #4A6E85; margin-bottom: 5px;
}
.auth-form input {
  width: 100%; padding: 10px 13px;
  background: #F5F9FB;
  border: 1.5px solid rgba(0,80,120,0.1);
  border-radius: 6px;
  color: #1C2A3A; font-family: var(--font-body); font-size: 0.9rem;
  transition: border-color 0.2s, box-shadow 0.2s;
  outline: none;
}
.auth-form input:focus {
  border-color: #4BB8D4; background: #fff;
  box-shadow: 0 0 0 3px rgba(75,184,212,0.12);
}
.auth-form input::placeholder { color: #ABCAD6; }

.btn-primary {
  padding: 11px 24px;
  background: linear-gradient(135deg, #1A7FA8, #2B9CC5);
  color: #fff; border: none; border-radius: 6px;
  font-family: var(--font-body); font-size: 0.9rem; font-weight: 600;
  cursor: pointer; transition: all 0.2s;
  box-shadow: 0 2px 8px rgba(26,127,168,0.2);
}
.btn-primary:hover {
  background: linear-gradient(135deg, #15698E, #2390B5);
  transform: translateY(-1px);
  box-shadow: 0 4px 14px rgba(26,127,168,0.3);
}
.auth-error {
  color: #C4473A; font-size: 0.82rem; text-align: center;
  min-height: 18px; margin-top: 6px;
}

/* Footer */
.auth-footer {
  text-align: center; padding: 20px;
  color: #6A8EA5; font-size: 0.76rem;
  border-top: 1px solid rgba(255,255,255,0.5);
}

/* Responsive */
@media (max-width: 960px) {
  .auth-hero-split { flex-direction: column; padding: 40px 24px 30px; min-height: auto; }
  .auth-hero-left { max-width: 100%; text-align: center; }
  .auth-hero-title { font-size: 2.2rem; }
  .auth-hero-btns { justify-content: center; }
  .auth-stats-ring { width: 340px; height: 340px; }
  .auth-ab-img { width: 180px; height: 180px; }
  .auth-stat-num { font-size: 1.8rem; }
  .auth-features-grid { grid-template-columns: repeat(2, 1fr); }
}
@media (max-width: 600px) {
  .auth-features-grid { grid-template-columns: 1fr; }
  .auth-hero-title { font-size: 1.8rem; }
  .auth-stats-ring { width: 280px; height: 280px; }
  .auth-ab-img { width: 140px; height: 140px; }
  .auth-stat-num { font-size: 1.4rem; }
  .auth-navbar { padding: 0 16px; }
  .auth-nav-tagline { display: none; }
}

/* ── MAIN APP ── */
.main-app {
  display: flex; height: 100vh; opacity: 0; pointer-events: none;
  transition: opacity 0.4s ease;
}
.main-app.active { opacity: 1; pointer-events: all; }

/* ── SIDEBAR ── */
.sidebar {
  width: var(--sidebar-w); height: 100vh;
  background: var(--navy);
  display: flex; flex-direction: column;
  transition: width var(--transition);
  position: relative; z-index: 10;
  flex-shrink: 0;
}
.sidebar.collapsed { width: var(--sidebar-collapsed); }

.sidebar-brand {
  display: flex; align-items: center; gap: 10px;
  padding: 16px 18px; border-bottom: 1px solid rgba(255,255,255,0.06);
  min-height: var(--header-h);
}
.brand-mark {
  width: 32px; height: 32px; border-radius: 8px;
  background: linear-gradient(135deg, var(--accent), #A86828);
  display: flex; align-items: center; justify-content: center;
  color: #fff; font-weight: 700; font-size: 0.85rem;
  flex-shrink: 0;
}
.brand-text { overflow: hidden; white-space: nowrap; }
.brand-text strong { color: #fff; font-size: 0.95rem; display: block; }
.brand-text small { color: rgba(255,255,255,0.35); font-size: 0.72rem; }
.sidebar.collapsed .brand-text { display: none; }

.sidebar-toggle {
  margin-left: auto; background: none; border: none;
  color: rgba(255,255,255,0.4); cursor: pointer; padding: 4px;
  transition: color var(--transition);
}
.sidebar-toggle:hover { color: var(--accent); }
.sidebar.collapsed .sidebar-toggle { margin-left: 0; }

.sidebar-nav {
  flex: 1; overflow-y: auto; padding: 12px 10px;
}
.nav-section { margin-bottom: 16px; }
.nav-label {
  display: block; font-size: 0.68rem; font-weight: 600;
  color: rgba(255,255,255,0.25); text-transform: uppercase;
  letter-spacing: 1px; padding: 4px 10px 8px;
}
.sidebar.collapsed .nav-label { display: none; }

.nav-item {
  display: flex; align-items: center; gap: 10px;
  width: 100%; padding: 9px 12px; border: none;
  background: none; color: rgba(255,255,255,0.55);
  font-family: var(--font-body); font-size: 0.85rem; font-weight: 500;
  border-radius: var(--radius-sm); cursor: pointer;
  transition: all var(--transition); text-align: left;
  white-space: nowrap;
}
.nav-item:hover { color: #fff; background: rgba(255,255,255,0.05); }
.nav-item.active { color: var(--accent); background: var(--teal-dim); }
.nav-item svg { flex-shrink: 0; }
.sidebar.collapsed .nav-item span { display: none; }
.sidebar.collapsed .nav-item { justify-content: center; padding: 9px; }

.sidebar-footer {
  padding: 12px 14px; border-top: 1px solid rgba(255,255,255,0.06);
}
.user-badge {
  display: flex; align-items: center; gap: 10px; margin-bottom: 8px;
}
.user-avatar {
  width: 32px; height: 32px; border-radius: 50%;
  background: linear-gradient(135deg, var(--accent), var(--purple));
  display: flex; align-items: center; justify-content: center;
  color: #fff; font-weight: 600; font-size: 0.82rem;
  flex-shrink: 0;
}
.user-info span { color: #fff; font-size: 0.82rem; font-weight: 500; display: block; }
.user-info small { color: rgba(255,255,255,0.35); font-size: 0.7rem; }
.sidebar.collapsed .user-info { display: none; }

.btn-logout {
  width: 100%; padding: 7px 12px; background: rgba(244,81,108,0.1);
  border: 1px solid rgba(244,81,108,0.2); border-radius: var(--radius-sm);
  color: var(--danger); font-family: var(--font-body); font-size: 0.78rem;
  cursor: pointer; transition: all var(--transition);
}
.btn-logout:hover { background: rgba(244,81,108,0.2); }
.sidebar.collapsed .btn-logout { font-size: 0; padding: 7px; }

/* ── CONTENT ── */
.content {
  flex: 1; overflow-y: auto; overflow-x: hidden;
  padding: 0;
  background:
    radial-gradient(ellipse at 20% 0%, rgba(0,191,166,0.03) 0%, transparent 50%),
    radial-gradient(ellipse at 80% 100%, rgba(155,109,255,0.02) 0%, transparent 50%),
    var(--surface-alt);
}

.page { display: none; padding: 28px 32px; animation: pageIn 0.35s ease-out; min-height: 100vh; }
.page.active { display: block; }

@keyframes pageIn {
  from { opacity: 0; transform: translateY(8px); }
  to { opacity: 1; transform: translateY(0); }
}

.page-header {
  display: flex; justify-content: space-between; align-items: flex-start;
  margin-bottom: 20px; flex-wrap: wrap; gap: 12px;
}
.page-header h2 {
  font-size: 1.5rem; font-weight: 700; color: var(--navy);
  letter-spacing: -0.3px;
}
.page-header h2 span { font-weight: 300; color: var(--text-muted); font-size: 1rem; margin-left: 8px; }
.page-header p { color: var(--text-muted); font-size: 0.82rem; margin-top: 4px; }

.header-actions { display: flex; align-items: center; gap: 8px; flex-wrap: wrap; }

/* ── BUTTONS ── */
.btn-accent {
  padding: 8px 16px; background: var(--teal-dim); color: var(--accent);
  border: 1px solid rgba(0,191,166,0.2); border-radius: var(--radius-sm);
  font-family: var(--font-body); font-size: 0.82rem; font-weight: 600;
  cursor: pointer; transition: all var(--transition);
}
.btn-accent:hover { background: rgba(0,191,166,0.2); }

.btn-ghost {
  padding: 8px 14px; background: none; color: var(--text-secondary);
  border: 1px solid var(--border); border-radius: var(--radius-sm);
  font-family: var(--font-body); font-size: 0.82rem; cursor: pointer;
  transition: all var(--transition);
}
.btn-ghost:hover { border-color: var(--accent); color: var(--accent); }

/* ── SELECTS & INPUTS ── */
.select-styled {
  padding: 8px 12px; border: 1px solid var(--border);
  border-radius: var(--radius-sm); background: var(--surface);
  font-family: var(--font-body); font-size: 0.82rem; color: var(--text);
  cursor: pointer; outline: none; transition: border-color var(--transition);
  min-width: 120px;
}
.select-styled:focus { border-color: var(--accent); }

.search-input {
  padding: 8px 14px; border: 1px solid var(--border);
  border-radius: var(--radius-sm); background: var(--surface);
  font-family: var(--font-body); font-size: 0.82rem; color: var(--text);
  outline: none; width: 220px; transition: border-color var(--transition);
}
.search-input:focus { border-color: var(--accent); }

/* ── SEQUENCE INPUT AREA ── */
.input-toolbar {
  display: flex; align-items: center; gap: 10px; margin-bottom: 16px;
}
.seq-counter { margin-left: auto; font-size: 0.82rem; color: var(--text-muted); }
.seq-counter strong { color: var(--accent); }

.seq-input-area { display: flex; flex-direction: column; gap: 12px; }

.empty-state {
  text-align: center; padding: 48px 20px; color: var(--text-muted);
  font-size: 0.85rem; line-height: 1.6;
}
.empty-state svg { margin-bottom: 12px; }

.seq-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 16px 20px;
  display: flex; flex-direction: column; gap: 12px;
  animation: cardIn 0.3s ease-out;
  position: relative;
  transition: border-color var(--transition);
}
.seq-card:hover { border-color: rgba(0,191,166,0.3); }

@keyframes cardIn {
  from { opacity: 0; transform: translateY(8px); }
  to { opacity: 1; transform: translateY(0); }
}

.seq-card-header {
  display: flex; align-items: center; gap: 12px;
}
.seq-num {
  width: 28px; height: 28px; border-radius: 50%;
  background: var(--teal-dim); color: var(--accent);
  display: flex; align-items: center; justify-content: center;
  font-size: 0.78rem; font-weight: 700; flex-shrink: 0;
}
.seq-card-header input[type="text"] {
  flex: 1; padding: 7px 10px; border: 1px solid var(--border);
  border-radius: var(--radius-sm); font-family: var(--font-body);
  font-size: 0.85rem; outline: none; transition: border-color var(--transition);
}
.seq-card-header input:focus { border-color: var(--accent); }
.seq-card-header select { min-width: 130px; }

.seq-remove {
  width: 28px; height: 28px; border-radius: 50%;
  background: none; border: 1px solid var(--border);
  color: var(--text-muted); cursor: pointer; display: flex;
  align-items: center; justify-content: center;
  transition: all var(--transition); font-size: 1.1rem;
}
.seq-remove:hover { background: rgba(244,81,108,0.1); border-color: var(--danger); color: var(--danger); }

.seq-card-body {
  display: grid; grid-template-columns: 1fr 1fr; gap: 10px;
}
.seq-textarea {
  width: 100%; padding: 10px 12px;
  border: 1px solid var(--border); border-radius: var(--radius-sm);
  font-family: var(--font-mono); font-size: 0.78rem; line-height: 1.5;
  resize: vertical; outline: none; min-height: 60px;
  transition: border-color var(--transition);
  background: var(--surface-alt);
}
.seq-textarea:focus { border-color: var(--accent); background: #fff; }
.seq-textarea::placeholder { color: var(--text-muted); font-family: var(--font-body); }

/* ── RESULTS & TABLES ── */
.results-area { min-height: 200px; }

.card-panel {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 20px 24px;
  margin-bottom: 16px;
}
.card-panel h3 {
  font-size: 1rem; font-weight: 600; color: var(--navy);
  margin-bottom: 16px; display: flex; align-items: center; gap: 8px;
}
.card-panel h3 .hint {
  font-size: 0.75rem; font-weight: 400; color: var(--text-muted);
}
.card-panel h4 {
  font-size: 0.88rem; font-weight: 600; color: var(--text-secondary);
  margin: 16px 0 10px; padding-top: 12px;
  border-top: 1px solid var(--border-light);
}

.form-row { display: flex; gap: 12px; flex-wrap: wrap; margin-bottom: 12px; }
.form-row-wrap { flex-wrap: wrap; }
.form-row .form-group { flex: 1; min-width: 160px; }
.form-group.fg-wide { flex: 3; min-width: 300px; }
.form-group label {
  display: block; font-size: 0.75rem; font-weight: 600;
  color: var(--text-secondary); margin-bottom: 5px;
  letter-spacing: 0.2px;
}

.info-badge {
  padding: 8px 12px; background: var(--surface-alt);
  border: 1px solid var(--border); border-radius: var(--radius-sm);
  font-size: 0.85rem; font-weight: 600; color: var(--text);
  text-align: center;
}

.data-table {
  width: 100%; border-collapse: collapse;
  font-size: 0.8rem;
}
.data-table thead { position: sticky; top: 0; z-index: 2; }
.data-table th {
  background: var(--navy); color: rgba(255,255,255,0.85);
  font-weight: 600; font-size: 0.72rem; text-transform: uppercase;
  letter-spacing: 0.5px; padding: 10px 12px; text-align: left;
  border-bottom: 2px solid var(--accent);
  white-space: nowrap; cursor: pointer;
  user-select: none;
}
.data-table th:hover { color: var(--accent); }
.data-table th.sorted-asc::after { content: ' ▲'; font-size: 0.6rem; }
.data-table th.sorted-desc::after { content: ' ▼'; font-size: 0.6rem; }

.data-table td {
  padding: 8px 12px; border-bottom: 1px solid var(--border-light);
  vertical-align: top; transition: background var(--transition);
}
.data-table tr:hover td { background: rgba(0,191,166,0.04); }

.data-table .seq-cell {
  font-family: var(--font-mono); font-size: 0.72rem;
  word-break: break-all; max-width: 300px; line-height: 1.4;
}

.data-table .validity-ok { color: var(--success); font-weight: 600; }
.data-table .validity-err { color: var(--danger); font-weight: 600; }

.liability-tag {
  display: inline-block; padding: 2px 6px; border-radius: 3px;
  font-size: 0.68rem; font-weight: 600; margin: 1px 2px;
}
.liability-tag.deam { background: rgba(255,184,34,0.15); color: #C98A00; }
.liability-tag.isom { background: rgba(155,109,255,0.12); color: var(--purple); }
.liability-tag.oxid { background: rgba(244,81,108,0.12); color: var(--danger); }
.liability-tag.cleav { background: rgba(0,191,166,0.12); color: #00897B; }
.liability-tag.glyco { background: rgba(30,136,229,0.12); color: #1565C0; }
.liability-tag.none { background: var(--surface-alt); color: var(--text-muted); }

/* VDomain result cards */
.vdomain-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); margin-bottom: 12px;
  overflow: hidden; animation: cardIn 0.3s ease-out;
}
.vdomain-card-head {
  display: flex; align-items: center; justify-content: space-between;
  padding: 12px 20px; background: var(--surface-alt);
  border-bottom: 1px solid var(--border-light);
  cursor: pointer;
}
.vdomain-card-head h4 { font-size: 0.92rem; font-weight: 600; }
.vdomain-card-head .status-pills { display: flex; gap: 6px; }
.vdomain-card-body { padding: 16px 20px; }

.vd-section { margin-bottom: 16px; }
.vd-section-title {
  font-size: 0.78rem; font-weight: 700; color: var(--navy);
  text-transform: uppercase; letter-spacing: 0.5px; margin-bottom: 10px;
  padding-bottom: 6px; border-bottom: 2px solid var(--accent);
  display: inline-block;
}

.seq-display {
  font-family: var(--font-mono); font-size: 0.76rem;
  line-height: 1.6; word-break: break-all;
  padding: 12px 14px; background: var(--surface-alt);
  border-radius: var(--radius-sm); border: 1px solid var(--border-light);
  margin-bottom: 10px;
}
.seq-display .aa-hydrophobic { color: #2196F3; }
.seq-display .aa-polar { color: #4CAF50; }
.seq-display .aa-positive { color: #F44336; }
.seq-display .aa-negative { color: #9C27B0; }
.seq-display .aa-special { color: #FF9800; }

.cdr-highlight { background: rgba(0,191,166,0.15); border-radius: 2px; padding: 0 1px; }

.liability-grid {
  display: grid; grid-template-columns: repeat(auto-fill, minmax(200px, 1fr));
  gap: 8px;
}
.liability-item {
  display: flex; align-items: center; gap: 8px;
  padding: 8px 10px; background: var(--surface-alt);
  border-radius: var(--radius-sm); border: 1px solid var(--border-light);
}
.liability-item .li-label { font-size: 0.75rem; color: var(--text-secondary); }
.liability-item .li-value { font-size: 0.82rem; font-weight: 600; margin-left: auto; }

/* ── MUTATION TOOL ── */
.mutation-grid {
  display: grid; grid-template-columns: repeat(5, 1fr); gap: 8px;
  margin-bottom: 16px;
}
.mutation-grid .form-group { min-width: 0; }
.mutation-grid input {
  width: 100%; padding: 8px 10px; border: 1px solid var(--border);
  border-radius: var(--radius-sm); font-family: var(--font-mono);
  font-size: 0.82rem; text-align: center; outline: none;
  text-transform: uppercase;
  transition: border-color var(--transition);
}
.mutation-grid input:focus { border-color: var(--accent); }
.mutation-grid input::placeholder { font-family: var(--font-body); font-size: 0.72rem; text-transform: none; }

.alignment-display {
  padding: 16px; background: var(--navy);
  border-radius: var(--radius); color: rgba(255,255,255,0.85);
  font-family: var(--font-mono); font-size: 0.72rem;
  line-height: 1.8; overflow-x: auto;
  margin-top: 12px;
}
.alignment-display .mut-highlight {
  background: rgba(155,109,255,0.4); color: #D4BBFF;
  padding: 0 2px; border-radius: 2px;
}
.alignment-display .region-label {
  color: var(--accent); font-weight: 600;
}

/* ── REFORMATTER ── */
.reformatter-seq-grid {
  display: grid; grid-template-columns: 1fr 1fr; gap: 10px;
  margin-bottom: 4px;
}

.rf-output-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 16px 20px;
  margin-bottom: 10px;
}
.rf-output-card h4 {
  font-size: 0.88rem; font-weight: 700; margin-bottom: 8px;
  border: none; padding: 0;
}
.rf-metrics {
  display: flex; gap: 20px; margin-bottom: 12px;
}
.rf-metric { text-align: center; }
.rf-metric .metric-val { font-size: 1.2rem; font-weight: 700; color: var(--accent); }
.rf-metric .metric-label { font-size: 0.7rem; color: var(--text-muted); }

/* ── INN TABLE ── */
.inn-table-wrapper {
  overflow: auto; max-height: calc(100vh - 180px);
  border: 1px solid var(--border); border-radius: var(--radius);
  background: var(--card);
}

.table-pagination {
  display: flex; align-items: center; justify-content: center;
  gap: 6px; padding: 12px; margin-top: 8px;
}
.table-pagination button {
  padding: 6px 12px; border: 1px solid var(--border);
  background: var(--card); border-radius: var(--radius-sm);
  font-family: var(--font-body); font-size: 0.78rem;
  cursor: pointer; transition: all var(--transition);
}
.table-pagination button:hover { border-color: var(--accent); color: var(--accent); }
.table-pagination button.active { background: var(--accent); color: #fff; border-color: var(--accent); }

/* ── CDR TABLE ── */
.cdr-scheme-section {
  margin-bottom: 20px;
}
.cdr-scheme-section h3 {
  font-size: 0.95rem; font-weight: 700; color: var(--navy);
  margin-bottom: 10px; display: flex; align-items: center; gap: 8px;
}
.cdr-scheme-section h3 .scheme-badge {
  padding: 3px 10px; background: var(--teal-dim);
  color: var(--accent); border-radius: 20px;
  font-size: 0.72rem; font-weight: 700;
}

.table-wrap {
  overflow-x: auto; border: 1px solid var(--border);
  border-radius: var(--radius); background: var(--card);
}

/* ── CHIMERA ── */
.chimera-result-row {
  display: grid; grid-template-columns: auto 1fr;
  gap: 8px 16px; align-items: start;
  padding: 12px 0; border-bottom: 1px solid var(--border-light);
}
.chimera-result-row:last-child { border-bottom: none; }
.chimera-label {
  font-size: 0.75rem; font-weight: 700; color: var(--text-secondary);
  text-transform: uppercase; letter-spacing: 0.3px;
  padding-top: 4px;
}

/* ── Responsive ── */
@media (max-width: 900px) {
  .sidebar { width: var(--sidebar-collapsed); }
  .sidebar .brand-text, .sidebar .nav-label,
  .sidebar .nav-item span, .sidebar .user-info { display: none; }
  .sidebar .nav-item { justify-content: center; padding: 9px; }
  .page { padding: 20px 16px; }
  .seq-card-body { grid-template-columns: 1fr; }
  .mutation-grid { grid-template-columns: repeat(2, 1fr); }
  .reformatter-seq-grid { grid-template-columns: 1fr; }
  .form-row { flex-direction: column; }
}

/* ── Copy button ── */
.copy-btn {
  padding: 4px 8px; background: var(--teal-dim); color: var(--accent);
  border: none; border-radius: 3px; font-size: 0.68rem; font-weight: 600;
  cursor: pointer; font-family: var(--font-body);
  transition: all var(--transition);
}
.copy-btn:hover { background: rgba(0,191,166,0.25); }

/* ── Analysis running indicator ── */
.analyzing {
  display: flex; align-items: center; gap: 10px;
  padding: 16px 20px; background: var(--teal-dim);
  border-radius: var(--radius); color: var(--accent);
  font-weight: 600; font-size: 0.88rem;
}
.analyzing::before {
  content: ''; width: 18px; height: 18px; border: 2px solid var(--accent);
  border-top-color: transparent; border-radius: 50%;
  animation: spin 0.8s linear infinite;
}
@keyframes spin { to { transform: rotate(360deg); } }

/* ── Toast notification ── */
.toast {
  position: fixed; bottom: 24px; right: 24px;
  padding: 12px 20px; background: var(--navy);
  color: #fff; border-radius: var(--radius-sm);
  font-size: 0.82rem; z-index: 9999;
  box-shadow: var(--shadow-lg);
  animation: toastIn 0.3s ease-out;
}
.toast.error { border-left: 3px solid var(--danger); }
.toast.success { border-left: 3px solid var(--success); }
@keyframes toastIn {
  from { opacity: 0; transform: translateY(10px); }
  to { opacity: 1; transform: translateY(0); }
}

/* ── INN Detail Panel ── */
.inn-detail-panel {
  margin-top: 8px;
  animation: pageIn 0.35s ease-out;
}
.inn-detail-header {
  display: flex; align-items: center; gap: 16px;
  margin-bottom: 20px; flex-wrap: wrap;
  padding-bottom: 16px;
  border-bottom: 2px solid var(--accent);
}
.inn-detail-header h3 {
  font-size: 1.3rem; font-weight: 700; color: var(--navy);
  flex: 1; text-transform: capitalize;
}

.inn-detail-grid {
  display: grid; grid-template-columns: 1fr 1fr; gap: 16px;
  margin-bottom: 20px;
}
@media (max-width: 900px) { .inn-detail-grid { grid-template-columns: 1fr; } }

.inn-detail-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); overflow: hidden;
}
.inn-detail-card.full-width { grid-column: 1 / -1; }
.inn-detail-card-head {
  padding: 10px 16px;
  background: var(--navy); color: #fff;
  font-size: 0.82rem; font-weight: 700;
  letter-spacing: 0.3px;
  display: flex; align-items: center; gap: 8px;
}
.inn-detail-card-head .tag {
  padding: 2px 8px; border-radius: 10px;
  font-size: 0.7rem; font-weight: 600;
  background: rgba(0,191,166,0.2); color: var(--teal-light);
}
.inn-detail-card-body { padding: 14px 16px; }

.inn-seq-label {
  font-size: 0.72rem; font-weight: 700; color: var(--text-secondary);
  text-transform: uppercase; letter-spacing: 0.5px;
  margin-bottom: 6px; display: flex; align-items: center; gap: 8px;
}
.inn-seq-label .seq-len {
  font-weight: 400; color: var(--text-muted); font-size: 0.7rem;
}

.inn-cdr-table {
  width: 100%; border-collapse: collapse; font-size: 0.78rem;
  margin-top: 8px;
}
.inn-cdr-table th {
  background: var(--surface-alt); color: var(--text-secondary);
  font-weight: 700; font-size: 0.7rem; text-transform: uppercase;
  letter-spacing: 0.3px; padding: 6px 10px; text-align: left;
  border-bottom: 1px solid var(--border);
}
.inn-cdr-table td {
  padding: 6px 10px; border-bottom: 1px solid var(--border-light);
  font-family: var(--font-mono); font-size: 0.76rem;
  word-break: break-all;
}
.inn-cdr-table .cdr-name { font-family: var(--font-body); font-weight: 700; color: var(--navy); }

.inn-props-grid {
  display: grid; grid-template-columns: repeat(auto-fill, minmax(140px, 1fr));
  gap: 8px;
}
.inn-prop {
  padding: 8px 10px; background: var(--surface-alt);
  border-radius: var(--radius-sm); border: 1px solid var(--border-light);
  text-align: center;
}
.inn-prop .prop-value { font-size: 1rem; font-weight: 700; color: var(--navy); }
.inn-prop .prop-label { font-size: 0.68rem; color: var(--text-muted); margin-top: 2px; }

.inn-row-clickable { cursor: pointer; }
.inn-row-clickable:hover td { background: var(--teal-dim) !important; }

/* highlighted CDR in sequence */
.cdr-region-h1 { background: rgba(33,150,243,0.15); border-radius: 2px; }
.cdr-region-h2 { background: rgba(76,175,80,0.15); border-radius: 2px; }
.cdr-region-h3 { background: rgba(244,81,108,0.15); border-radius: 2px; }
.cdr-region-l1 { background: rgba(33,150,243,0.15); border-radius: 2px; }
.cdr-region-l2 { background: rgba(76,175,80,0.15); border-radius: 2px; }
.cdr-region-l3 { background: rgba(244,81,108,0.15); border-radius: 2px; }

.seq-display-annotated {
  font-family: var(--font-mono); font-size: 0.74rem;
  line-height: 1.7; word-break: break-all;
  padding: 12px 14px; background: var(--surface-alt);
  border-radius: var(--radius-sm); border: 1px solid var(--border-light);
  margin-bottom: 6px;
}
.cdr-legend {
  display: flex; gap: 12px; font-size: 0.7rem; margin-top: 4px; color: var(--text-muted);
}
.cdr-legend span { display: flex; align-items: center; gap: 4px; }
.cdr-legend .swatch {
  width: 12px; height: 12px; border-radius: 2px; display: inline-block;
}

/* ── Humanization Module ── */
.hz-input-panel {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 20px 24px; margin-bottom: 20px;
}
.hz-input-row {
  display: flex; gap: 16px; align-items: flex-end; flex-wrap: wrap;
}
.hz-input-row .form-group { flex: 1; min-width: 200px; }
.hz-input-row .btn-primary { height: 40px; white-space: nowrap; margin-bottom: 0; }
.hz-manual-inputs { display: grid; grid-template-columns: 1fr 1fr; gap: 16px; margin-top: 16px; }
.hz-manual-hint {
  font-size: 0.75rem; color: var(--text-muted); margin-top: 8px; line-height: 1.5;
}
.hz-info-box {
  text-align: left; max-width: 600px; margin: 20px auto 0;
  background: var(--surface-alt); border: 1px solid var(--border-light);
  border-radius: var(--radius-sm); padding: 16px 20px; font-size: 0.8rem;
  line-height: 1.7; color: var(--text-secondary);
}
.hz-info-box strong { color: var(--accent); display: block; margin-bottom: 8px; }
.hz-info-box ul { margin: 4px 0 10px 16px; padding: 0; }
.hz-info-box li { margin-bottom: 2px; }

/* Candidate cards */
.hz-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); margin-bottom: 12px; overflow: hidden;
  animation: cardIn 0.3s ease-out;
}
.hz-card-head {
  display: flex; align-items: center; gap: 12px;
  padding: 12px 18px; cursor: pointer;
  transition: background 0.2s;
}
.hz-card-head:hover { background: rgba(255,255,255,0.03); }
.hz-rank {
  font-weight: 700; font-size: 0.9rem; color: var(--accent);
  background: var(--teal-dim); padding: 2px 8px; border-radius: 4px;
}
.hz-germ {
  font-weight: 600; font-size: 0.85rem; color: var(--text-primary);
  font-family: var(--font-mono);
}
.hz-score {
  font-size: 0.75rem; color: var(--text-muted); margin-left: auto;
}
.hz-bar-wrap {
  position: relative; height: 6px; background: var(--surface-alt);
  margin: 0 18px 0;
}
.hz-bar {
  height: 100%; background: linear-gradient(90deg, var(--accent), #4dd0e1);
  border-radius: 3px; transition: width 0.6s ease;
}
.hz-bar-label {
  position: absolute; right: 0; top: -16px; font-size: 0.65rem;
  color: var(--accent); font-weight: 600;
}
.hz-card-body {
  padding: 16px 18px; border-top: 1px solid var(--border-light);
  transition: max-height 0.3s ease;
}
.hz-card-body.collapsed { display: none; }
.hz-section { margin-bottom: 16px; }
.hz-section h5 {
  font-size: 0.78rem; font-weight: 600; color: var(--text-secondary);
  margin-bottom: 8px; text-transform: uppercase; letter-spacing: 0.5px;
}
.hz-hint {
  font-size: 0.72rem; color: var(--text-muted); margin-bottom: 8px;
  font-style: italic;
}

/* Alignment display */
.hz-align-region {
  margin-bottom: 8px; padding: 6px 0;
  border-bottom: 1px solid var(--border-light);
}
.hz-align-region:last-child { border-bottom: none; }
.hz-align-label {
  font-size: 0.7rem; font-weight: 700; color: var(--accent);
  margin-bottom: 4px; text-transform: uppercase;
}
.hz-align-row {
  font-family: var(--font-mono); font-size: 0.72rem;
  line-height: 1.8; word-break: break-all;
}
.hz-row-label {
  display: inline-block; width: 50px; font-weight: 600;
  color: var(--text-muted); font-size: 0.68rem;
}
.hz-aa {
  display: inline-block; width: 1em; text-align: center;
  color: var(--text-secondary);
}
.hz-aa.hz-diff {
  background: rgba(244, 81, 108, 0.25); color: #f4516c;
  font-weight: 700; border-radius: 2px;
}

/* Sequence box */
.hz-seq-box {
  background: var(--surface-alt); border: 1px solid var(--border-light);
  border-radius: var(--radius-sm); padding: 10px 14px;
  font-family: var(--font-mono); font-size: 0.72rem;
  line-height: 1.7; word-break: break-all; color: var(--text-secondary);
  margin-bottom: 8px;
}
.hz-copy-btn {
  background: var(--teal-dim); color: var(--accent); border: none;
  padding: 4px 12px; border-radius: 4px; cursor: pointer;
  font-size: 0.72rem; font-weight: 600; transition: all 0.2s;
}
.hz-copy-btn:hover { background: var(--accent); color: var(--bg); }

/* Back-mutation table */
.hz-table {
  width: 100%; border-collapse: collapse; font-size: 0.75rem;
}
.hz-table th {
  text-align: left; padding: 6px 10px; font-weight: 600;
  background: var(--surface-alt); color: var(--text-muted);
  border-bottom: 1px solid var(--border);
  font-size: 0.7rem; text-transform: uppercase;
}
.hz-table td {
  padding: 5px 10px; border-bottom: 1px solid var(--border-light);
  color: var(--text-secondary);
}
.hz-table tr:hover td { background: rgba(0,191,166,0.04); }
.hz-aa-cell {
  font-family: var(--font-mono); font-weight: 700; text-align: center;
  font-size: 0.8rem;
}

/* Export button */
.hz-export-btn {
  background: var(--accent); color: var(--bg); border: none;
  padding: 8px 20px; border-radius: var(--radius-sm); cursor: pointer;
  font-weight: 600; font-size: 0.8rem; transition: all 0.2s;
}
.hz-export-btn:hover { opacity: 0.85; transform: translateY(-1px); }

/* Enhanced scoring */
.hz-enhanced-scores { border-bottom: 1px solid var(--border-light); padding-bottom: 12px; }
.hz-score-grid { display: flex; gap: 24px; flex-wrap: wrap; }
.hz-score-item { display: flex; flex-direction: column; gap: 2px; }
.hz-score-val { font-size: 1.1rem; font-weight: 700; color: var(--accent); }
.hz-score-lbl { font-size: 0.68rem; color: var(--text-muted); }
.hz-risk-low { color: #4CAF50 !important; }
.hz-risk-med { color: #FF9800 !important; }
.hz-risk-high { color: #F4516C !important; }

/* ── Structure Prediction Module ── */
.str-input-panel {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 20px 24px; margin-bottom: 20px;
}
.str-input-row {
  display: flex; gap: 16px; align-items: flex-end; flex-wrap: wrap;
}
.str-input-row .form-group { flex: 1; min-width: 250px; }
.str-input-row .btn-primary { height: 40px; white-space: nowrap; }
.str-upload-row {
  margin-top: 12px; padding-top: 12px; border-top: 1px solid var(--border-light);
}
.str-upload-label {
  font-size: 0.78rem; color: var(--text-muted); cursor: pointer;
  display: flex; align-items: center; gap: 8px;
}
.str-file-input-inline { font-size: 0.75rem; }
.str-result-container { min-height: 200px; }
.str-result-head {
  display: flex; justify-content: space-between; align-items: center;
  padding: 10px 0; margin-bottom: 8px; flex-wrap: wrap; gap: 8px;
  font-weight: 600; color: var(--text-primary); font-size: 0.85rem;
}
.str-controls { display: flex; gap: 6px; flex-wrap: wrap; }
.str-ctrl-btn {
  background: var(--surface-alt); border: 1px solid var(--border);
  color: var(--text-secondary); padding: 4px 10px; border-radius: 4px;
  cursor: pointer; font-size: 0.72rem; transition: all 0.2s;
}
.str-ctrl-btn:hover { background: var(--teal-dim); color: var(--accent); border-color: var(--accent); }
.str-viewer-box {
  width: 100%; height: 500px;
  background: #0a1628; border-radius: var(--radius);
  border: 1px solid var(--border); position: relative;
}
.str-cdr-legend {
  display: flex; gap: 14px; margin-top: 8px; font-size: 0.72rem; color: var(--text-muted);
  flex-wrap: wrap;
}
.str-cdr-legend span { display: flex; align-items: center; gap: 4px; }
.str-cdr-legend i {
  width: 12px; height: 12px; border-radius: 2px; display: inline-block;
}
.str-loading {
  display: flex; flex-direction: column; align-items: center;
  justify-content: center; padding: 60px 20px; text-align: center;
}
.str-spinner {
  width: 40px; height: 40px;
  border: 3px solid var(--border); border-top-color: var(--accent);
  border-radius: 50%; animation: spin 0.8s linear infinite;
  margin-bottom: 16px;
}
@keyframes spin { to { transform: rotate(360deg); } }
.str-loading p { color: var(--text-secondary); font-size: 0.85rem; margin: 4px 0; }
.str-hint { color: var(--text-muted) !important; font-size: 0.75rem !important; }
.str-error {
  padding: 24px; background: var(--card); border: 1px solid var(--border);
  border-radius: var(--radius); color: var(--text-secondary); font-size: 0.82rem;
}
.str-error p:first-child { color: #F4516C; font-weight: 600; margin-bottom: 12px; }
.str-error ul { margin: 8px 0 16px 20px; }
.str-error li { margin-bottom: 6px; }
.str-error a { color: var(--accent); text-decoration: underline; }
.str-upload-area {
  margin-top: 12px; padding: 20px; text-align: center;
  border: 2px dashed var(--border); border-radius: var(--radius);
  cursor: pointer; transition: all 0.2s; color: var(--text-muted);
}
.str-upload-area:hover { border-color: var(--accent); color: var(--accent); }
.str-upload-area input[type="file"] { display: block; margin: 8px auto 0; }

/* ── Payment Modal ── */
.payment-modal-overlay {
  position: fixed; inset: 0;
  background: rgba(11,29,58,0.7);
  backdrop-filter: blur(6px);
  display: none; align-items: center; justify-content: center;
  z-index: 10000;
}
.payment-modal-overlay.active { display: flex; }
.payment-modal {
  background: var(--surface); border-radius: var(--radius);
  width: 90%; max-width: 440px;
  box-shadow: var(--shadow-lg);
  animation: pageIn 0.3s ease-out;
  overflow: hidden;
}
.payment-modal-header {
  display: flex; justify-content: space-between; align-items: center;
  padding: 16px 20px;
  background: var(--navy); color: #fff;
}
.payment-modal-header h3 { font-size: 1rem; font-weight: 700; }
.payment-close {
  background: none; border: none; color: #fff;
  font-size: 1.4rem; cursor: pointer; opacity: 0.7;
}
.payment-close:hover { opacity: 1; }
.payment-modal-body { padding: 20px; }
.payment-price-display {
  text-align: center; padding: 16px 0 12px;
}
.payment-currency {
  font-size: 1.2rem; font-weight: 700; color: var(--accent);
  vertical-align: super;
}
.payment-amount {
  font-size: 3rem; font-weight: 800; color: var(--navy);
  line-height: 1;
}
.payment-period { font-size: 0.85rem; color: var(--text-muted); }
.payment-features {
  list-style: none; padding: 0; margin: 12px 0 20px;
}
.payment-features li {
  padding: 6px 0 6px 22px; font-size: 0.82rem;
  color: var(--text-secondary); position: relative;
}
.payment-features li::before {
  content: '✓'; position: absolute; left: 0;
  color: var(--accent); font-weight: 700;
}
.payment-methods { margin-top: 12px; }
.payment-methods h4 {
  font-size: 0.78rem; color: var(--text-muted);
  text-transform: uppercase; letter-spacing: 0.3px;
  margin-bottom: 10px;
}
.payment-method-btn {
  display: flex; align-items: center; gap: 10px;
  width: 100%; padding: 12px 16px; margin-bottom: 8px;
  background: var(--surface-alt); border: 1.5px solid var(--border);
  border-radius: var(--radius-sm); cursor: pointer;
  font-size: 0.88rem; font-weight: 600; color: var(--text);
  transition: var(--transition);
}
.payment-method-btn:hover {
  border-color: var(--accent); background: var(--teal-dim);
}
.payment-status {
  margin-top: 16px; padding: 12px; border-radius: var(--radius-sm);
  font-size: 0.82rem; text-align: center;
}
.payment-status.loading { color: var(--text-muted); }
.payment-status.success { background: rgba(43,196,138,0.1); color: var(--success); }
.payment-status.error { background: rgba(244,81,108,0.1); color: var(--danger); }
.payment-status .btn-primary { margin-top: 8px; }

/* ── Structure Manual Input ── */
.str-hz-pair-section .str-input-row {
  align-items: flex-end;
}
.str-divider {
  text-align: center; margin: 18px 0 14px;
  position: relative;
}
.str-divider::before {
  content: ''; position: absolute; left: 0; top: 50%;
  width: 100%; height: 1px; background: var(--border);
}
.str-divider span {
  position: relative; background: var(--surface);
  padding: 0 14px; font-size: 0.82rem; color: var(--text-muted);
}
.str-manual-input {
  background: var(--surface-alt); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 16px; margin-bottom: 14px;
}
.str-manual-row { margin-bottom: 10px; display: flex; gap: 12px; }
.str-manual-row:last-of-type { margin-bottom: 14px; }
.str-manual-input .seq-textarea {
  font-family: 'JetBrains Mono', monospace; font-size: 0.82rem;
  width: 100%; resize: vertical;
}
.str-ctrl-sep {
  color: var(--border); margin: 0 2px; font-size: 0.9rem;
  user-select: none;
}
.str-mode-btn.active {
  background: var(--accent); color: #fff; border-color: var(--accent);
}
.str-props-panel {
  margin-top: 16px; background: var(--surface-alt);
  border: 1px solid var(--border); border-radius: var(--radius);
  padding: 16px;
}
.str-props-panel h4 {
  font-size: 0.85rem; font-weight: 700; color: var(--text);
  margin-bottom: 12px; letter-spacing: 0.3px;
}
.str-props-grid {
  display: grid; grid-template-columns: repeat(auto-fill, minmax(180px, 1fr));
  gap: 10px;
}
.str-prop {
  display: flex; justify-content: space-between; align-items: center;
  background: var(--surface); border: 1px solid var(--border);
  border-radius: var(--radius-sm); padding: 8px 12px;
}
.str-prop-label {
  font-size: 0.78rem; color: var(--text-secondary);
}
.str-prop-val {
  font-size: 0.88rem; font-weight: 700; color: var(--text);
  font-family: 'JetBrains Mono', monospace;
}
.str-prop-val.pos { color: #2B5FE0; }
.str-prop-val.neg { color: #E02B2B; }
.str-legend-title {
  font-size: 0.78rem; font-weight: 600; color: var(--text-secondary);
  margin-right: 8px; letter-spacing: 0.2px;
}
.str-view-btn { font-size: 0.75rem !important; }

/* ── Advanced Analysis ── */
.adv-tabs {
  display: flex; gap: 4px; margin-bottom: 20px;
  border-bottom: 2px solid var(--border); padding-bottom: 0;
}
.adv-tab {
  padding: 10px 20px; background: none; border: none;
  font-size: 0.88rem; font-weight: 600; color: var(--text-secondary);
  cursor: pointer; border-bottom: 2px solid transparent;
  margin-bottom: -2px; transition: var(--transition);
  font-family: var(--font-body);
}
.adv-tab:hover { color: var(--text); }
.adv-tab.active {
  color: var(--accent); border-bottom-color: var(--accent);
}
.adv-panel { display: none; }
.adv-panel.active { display: block; }
.adv-input-bar {
  display: flex; align-items: flex-end; gap: 12px;
  margin-bottom: 16px; flex-wrap: wrap;
}
.adv-input-bar .form-group { margin-bottom: 0; min-width: 140px; }
.adv-manual-section {
  margin: 8px 0 12px;
  padding: 12px;
  background: var(--surface);
  border: 1px solid var(--border-light);
  border-radius: var(--radius);
}
.adv-manual-section label {
  display: block; font-size: 0.82rem; font-weight: 600;
  color: var(--text-secondary); margin-bottom: 6px;
}
.adv-manual-section .seq-textarea {
  width: 100%; font-size: 0.82rem;
}
.adv-results {
  background: var(--surface); border: 1px solid var(--border);
  border-radius: var(--radius); padding: 16px;
  min-height: 120px;
}
.adv-empty, .adv-loading {
  text-align: center; color: var(--text-muted);
  padding: 40px 20px; font-size: 0.88rem;
}
.adv-loading { color: var(--accent); }
.msa-wrapper { border-radius: var(--radius-sm); }

/* ── Nanobody Humanization ── */
.nb-info-box {
  text-align: left;
}
.nb-diff-grid {
  display: grid; grid-template-columns: 1fr 1fr;
  gap: 16px; margin: 16px 0;
}
.nb-diff-item {
  background: var(--surface);
  border: 1px solid var(--border-light);
  border-radius: var(--radius);
  padding: 14px;
}
.nb-diff-title {
  font-weight: 700; font-size: 0.88rem;
  color: var(--accent); margin-bottom: 6px;
}
.nb-diff-item p {
  font-size: 0.82rem; line-height: 1.5;
  color: var(--text-secondary); margin: 4px 0;
}
.nb-ref-box {
  background: var(--surface);
  border: 1px solid var(--border-light);
  border-radius: var(--radius);
  padding: 14px; margin-top: 12px;
}
.nb-ref-box ol {
  padding-left: 20px; margin-top: 8px;
}
.nb-ref-box li {
  font-size: 0.8rem; color: var(--text-secondary);
  line-height: 1.5; margin-bottom: 4px;
}
.nb-ref-box em { font-style: italic; }
.nb-hallmark-badge {
  display: inline-block;
  padding: 2px 8px;
  border-radius: 10px;
  font-size: 0.75rem;
  font-weight: 600;
  font-family: var(--font-mono);
}
.nb-hallmark-preserved {
  background: rgba(58,140,92,0.12);
  color: var(--success);
  border: 1px solid rgba(58,140,92,0.25);
}
.nb-hallmark-humanized {
  background: rgba(196,71,58,0.12);
  color: var(--danger);
  border: 1px solid rgba(196,71,58,0.25);
}
.nb-hallmark-table {
  width: 100%; border-collapse: collapse;
  font-size: 0.82rem; margin: 8px 0;
}
.nb-hallmark-table th {
  background: var(--surface-alt);
  padding: 6px 10px; text-align: left;
  border-bottom: 2px solid var(--border);
  font-weight: 600; color: var(--text-secondary);
}
.nb-hallmark-table td {
  padding: 5px 10px;
  border-bottom: 1px solid var(--border-light);
  font-family: var(--font-mono);
}
.nb-hallmark-table tr:hover { background: var(--surface); }
.nb-strategy-tag {
  display: inline-block;
  padding: 3px 10px; border-radius: 12px;
  font-size: 0.78rem; font-weight: 600;
  margin-left: 8px;
}
.nb-strategy-preserve {
  background: rgba(58,140,92,0.12); color: var(--success);
}
.nb-strategy-partial {
  background: rgba(212,148,58,0.12); color: var(--warning);
}
.nb-strategy-full {
  background: rgba(196,71,58,0.12); color: var(--danger);
}
.nb-cdr3-info {
  display: flex; gap: 16px; align-items: center;
  padding: 8px 12px; background: var(--surface);
  border-radius: var(--radius-sm); margin: 8px 0;
  font-size: 0.82rem;
}
.nb-cdr3-info .label { color: var(--text-secondary); }
.nb-cdr3-info .value { font-weight: 700; font-family: var(--font-mono); }
.nb-cdr3-info .warn { color: var(--warning); font-weight: 600; }
@media (max-width: 900px) {
  .nb-diff-grid { grid-template-columns: 1fr; }
}

/* ── Llamanade PPM Analysis Styles ── */
.nb-analysis-summary {
  display: flex; flex-wrap: wrap; gap: 6px; margin: 10px 0;
}
.nb-sum-chip {
  display: inline-block; padding: 3px 10px; border-radius: 12px;
  font-size: 0.75rem; font-weight: 600; font-family: var(--font-mono);
}
.nb-sum-identical { background: var(--surface-alt); color: var(--text-secondary); }
.nb-sum-humanized { background: rgba(231,76,60,0.12); color: #e74c3c; border: 1px solid rgba(231,76,60,0.2); }
.nb-sum-ppm { background: rgba(52,152,219,0.12); color: #3498db; border: 1px solid rgba(52,152,219,0.2); }
.nb-sum-buried { background: rgba(149,165,166,0.15); color: #7f8c8d; border: 1px solid rgba(149,165,166,0.2); }
.nb-sum-hallmark { background: rgba(58,140,92,0.12); color: var(--success); border: 1px solid rgba(58,140,92,0.2); }
.nb-sum-intra { background: rgba(155,89,182,0.12); color: #9b59b6; border: 1px solid rgba(155,89,182,0.2); }

.nb-ppm-table th { font-size: 0.75rem; text-transform: uppercase; letter-spacing: 0.3px; }
.nb-ppm-table td { font-size: 0.78rem; }

.nb-row-humanized { background: rgba(231,76,60,0.05); }
.nb-row-humanized:hover { background: rgba(231,76,60,0.10); }
.nb-row-hallmark { background: rgba(58,140,92,0.05); }
.nb-row-hallmark:hover { background: rgba(58,140,92,0.10); }
.nb-row-buried { background: rgba(149,165,166,0.05); }
.nb-row-buried:hover { background: rgba(149,165,166,0.10); }
.nb-row-intra { background: rgba(155,89,182,0.05); }
.nb-row-intra:hover { background: rgba(155,89,182,0.10); }
.nb-row-kept { background: rgba(52,152,219,0.04); }
.nb-row-kept:hover { background: rgba(52,152,219,0.08); }

.nb-action-humanized {
  background: rgba(231,76,60,0.12); color: #e74c3c;
  border: 1px solid rgba(231,76,60,0.25);
}
.nb-action-kept_ppm {
  background: rgba(52,152,219,0.12); color: #3498db;
  border: 1px solid rgba(52,152,219,0.25);
}
.nb-action-kept_buried {
  background: rgba(149,165,166,0.15); color: #7f8c8d;
  border: 1px solid rgba(149,165,166,0.25);
}
.nb-action-kept_hallmark {
  background: rgba(58,140,92,0.12); color: var(--success);
  border: 1px solid rgba(58,140,92,0.25);
}
.nb-action-kept_intramolecular {
  background: rgba(155,89,182,0.12); color: #9b59b6;
  border: 1px solid rgba(155,89,182,0.25);
}

.nb-t20-section .hz-score-grid {
  grid-template-columns: repeat(4, 1fr);
}

.msa-wrapper svg { display: block; }

/* ============================================================
   FORMAT REFERENCE TABLE
   ============================================================ */
.format-ref-table {
  width: 100%; border-collapse: collapse; font-size: 0.78rem;
}
.format-ref-table th {
  background: var(--navy); color: #fff; padding: 8px 10px;
  text-align: left; font-weight: 600; font-size: 0.72rem;
  letter-spacing: 0.03em; position: sticky; top: 0; z-index: 1;
}
.format-ref-table td {
  padding: 6px 10px; border-bottom: 1px solid var(--border-light);
}
.format-ref-table .fmt-row { cursor: pointer; transition: background 0.15s; }
.format-ref-table .fmt-row:hover { background: rgba(0,191,166,0.08); }
.format-ref-table .fmt-id { font-weight: 700; color: var(--teal); min-width: 32px; }
.format-ref-table .fmt-name { font-weight: 500; white-space: nowrap; }
.format-ref-table .fmt-val { text-align: center; font-weight: 600; }
.format-ref-table .fmt-comp { font-family: 'JetBrains Mono', monospace; font-size: 0.7rem; color: var(--text-muted); max-width: 320px; word-break: break-all; }
.format-ref-table .fmt-svg { padding: 4px 6px; min-width: 80px; text-align: center; }
.format-ref-table .fmt-svg svg { display: inline-block; max-height: 48px; }
.fmt-spec-badge {
  display: inline-block; padding: 2px 8px; border-radius: 10px;
  font-size: 0.68rem; font-weight: 600; letter-spacing: 0.03em;
}
.fmt-spec-badge.spec-mono { background: rgba(0,191,166,0.15); color: var(--teal); }
.fmt-spec-badge.spec-bi { background: rgba(99,102,241,0.15); color: #6366f1; }
.fmt-spec-badge.spec-tri { background: rgba(245,158,11,0.15); color: #f59e0b; }
.fmt-fc-yes { color: var(--teal); font-weight: 700; font-size: 0.75rem; }
.fmt-fc-no { color: var(--text-muted); }

/* ============================================================
   PATENT SEQUENCE EXTRACTION MODULE
   ============================================================ */
.pat-upload-panel { padding: 0; overflow: hidden; }
.pat-upload-zone {
  display: flex; flex-direction: column; align-items: center; justify-content: center;
  padding: 48px 24px; border: 2px dashed var(--border); border-radius: var(--radius);
  cursor: pointer; transition: all 0.25s ease; text-align: center; margin: 16px;
  background: repeating-linear-gradient(135deg, transparent, transparent 10px, rgba(212,136,58,0.03) 10px, rgba(212,136,58,0.03) 20px);
}
.pat-upload-zone:hover, .pat-upload-zone.pat-drag-over {
  border-color: var(--accent); background: rgba(212,136,58,0.06);
}
.pat-drop-text { margin: 12px 0 4px; font-size: 0.95rem; color: var(--text-primary); }
.pat-browse-link { color: var(--accent); cursor: pointer; text-decoration: underline; font-weight: 600; }
.pat-drop-hint { font-size: 0.8rem; color: var(--text-secondary); }
.pat-file-info {
  display: flex; align-items: center; gap: 12px; padding: 12px 20px;
  background: var(--surface-2); border-top: 1px solid var(--border); font-size: 0.85rem;
}
.pat-file-info #patFileName { font-weight: 600; color: var(--accent); }
.pat-file-info #patFileSize { color: var(--text-secondary); }
.pat-clear-btn { margin-left: auto; font-size: 0.8rem; }

.pat-options-panel h4 { margin-bottom: 14px; }
.pat-options-row {
  display: grid; grid-template-columns: repeat(auto-fit, minmax(160px, 1fr)); gap: 14px;
}
.pat-actions-row { display: flex; gap: 12px; margin-top: 18px; }

.pat-progress-panel { padding: 20px 24px; }
.pat-progress-bar {
  height: 6px; background: var(--surface-2); border-radius: 3px; overflow: hidden;
}
.pat-progress-fill {
  height: 100%; background: linear-gradient(90deg, var(--accent), var(--teal));
  border-radius: 3px; transition: width 0.3s ease; width: 0%;
}
.pat-progress-text { margin-top: 8px; font-size: 0.85rem; color: var(--text-secondary); }

.pat-summary-panel h4 { margin-bottom: 12px; }
.pat-summary-chips { display: flex; flex-wrap: wrap; gap: 8px; }
.pat-chip {
  display: inline-flex; align-items: center; padding: 4px 12px; border-radius: 20px;
  font-size: 0.78rem; font-weight: 600;
}
.pat-chip-total { background: var(--surface-2); color: var(--text-primary); }
.pat-chip-protein { background: rgba(0,191,166,0.12); color: var(--teal); }
.pat-chip-nt { background: rgba(100,140,255,0.12); color: #648cff; }
.pat-chip-3letter { background: rgba(212,136,58,0.12); color: var(--accent); }
.pat-chip-seqid { background: rgba(168,85,247,0.12); color: #a855f7; }
.pat-chip-type { background: var(--surface-2); color: var(--text-secondary); }
.pat-chip-ocr { background: rgba(239,68,68,0.12); color: #ef4444; }

.pat-ocr-options {
  margin-top: 14px; padding-top: 14px; border-top: 1px solid var(--border);
}
.pat-ocr-hint {
  margin-top: 10px; font-size: 0.78rem; color: var(--text-secondary);
  line-height: 1.5; background: rgba(239,68,68,0.04); padding: 10px 14px;
  border-radius: var(--radius); border-left: 3px solid rgba(239,68,68,0.3);
}

.pat-results-head {
  display: flex; flex-wrap: wrap; align-items: center; gap: 12px; margin-bottom: 16px;
}
.pat-results-head h4 { margin: 0; flex: 1; }
.pat-results-actions { display: flex; flex-wrap: wrap; gap: 8px; }
.pat-filter-active { background: var(--accent) !important; color: #fff !important; }

.pat-seq-table {
  width: 100%; border-collapse: collapse; font-size: 0.82rem;
}
.pat-seq-table thead { position: sticky; top: 0; z-index: 1; }
.pat-seq-table th {
  padding: 8px 10px; text-align: left; background: var(--surface-2);
  border-bottom: 2px solid var(--border); font-weight: 600; white-space: nowrap;
  font-size: 0.78rem; text-transform: uppercase; letter-spacing: 0.04em;
}
.pat-seq-table td {
  padding: 7px 10px; border-bottom: 1px solid var(--border); vertical-align: middle;
}
.pat-seq-table tbody tr:hover { background: rgba(212,136,58,0.04); }
.pat-type-badge {
  display: inline-block; padding: 2px 8px; border-radius: 10px;
  font-size: 0.72rem; font-weight: 700; letter-spacing: 0.05em;
}
.pat-type-protein { background: rgba(0,191,166,0.15); color: var(--teal); }
.pat-type-nt { background: rgba(100,140,255,0.15); color: #648cff; }
.pat-class-cell { max-width: 140px; font-size: 0.78rem; }
.pat-format-cell { font-size: 0.75rem; color: var(--text-secondary); }
.pat-seq-cell { max-width: 280px; overflow: hidden; }
.pat-seq-code {
  font-family: 'JetBrains Mono', monospace; font-size: 0.72rem; word-break: break-all;
  color: var(--text-primary); background: var(--surface-2); padding: 2px 6px; border-radius: 4px;
}
.pat-actions-cell { white-space: nowrap; }
.pat-copy-btn { font-size: 0.75rem !important; padding: 2px 8px !important; }
.pat-results-table-wrap { max-height: 500px; overflow-y: auto; }

.pat-text-panel h4 { display: flex; align-items: center; gap: 12px; }
.pat-toggle-text { font-size: 0.8rem; }
.pat-source-pre {
  font-family: 'JetBrains Mono', monospace; font-size: 0.72rem; line-height: 1.5;
  white-space: pre-wrap; word-break: break-all; max-height: 400px; overflow-y: auto;
  padding: 16px; background: var(--surface-2); border-radius: var(--radius);
  color: var(--text-secondary);
}
.pat-empty { text-align: center; padding: 24px; color: var(--text-secondary); font-style: italic; }